Description
Antibody Name: | Mouse CD14 Monoclonal Antibody (PE Conjugated) |
Antibody Code: | AGEL1864 |
Size: | 100 Tests |
Clone: | Sa14-2 |
Synonyms: | CD 14,Myeloid cell-specific leucine-rich glycoprotein,Monocyte differentiation antigen CD14 |
Host Species: | Rat |
Species Reactivity: | Mouse |
Applications: | FC |
Concentration: | 5uL |
Isotype: | IgG2a,k |
Conjugation: | PE |
Applications: | FC |
Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Storage Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. |
Gene ID: | 12475 |
Uniprot: | P10810 |
Background: | CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens. |
Mouse abdominal macrophages elicited by starch broth are stained with Anti-Mouse CD14 Monoclonal Antibody(PE Conjugated)(filled gray curve). Unstained macrophages (blank black curve) are used as control. |