](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/11042/15096/mouse-cd127-monoclonal-antibody-pe-conjugated-a7r34agel0130__82488__60859.1706269328.jpg?c=1?imbypass=on "Mouse CD127 Monoclonal Antibody (PE Conjugated) [A7R34](AGEL0130)")
Description
system_update_altDatasheet
| Antibody Name: | Mouse CD127 Monoclonal Antibody (PE Conjugated) |
| Antibody Code: | AGEL0130 |
| Size: | 50 Tests |
| Clone: | A7R34 |
| Synonyms: | Interleukin-7 receptor subunit alpha, Il7r, IL-7 receptor subunit alpha, IL-7R subunit alpha, IL-7R-alpha, IL-7RA, CD127 |
| Host Species: | Rat |
| Species Reactivity: | Mouse |
| Applications: | FC |
| Concentration: | 5uL |
| Isotype: | IgG2a |
| Conjugation: | PE |
| Applications: | FC |
| Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| Storage Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Storage: | Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Gene ID: | 16197 |
| Uniprot: | P16872 |
| Background: | CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor Ī± chain or IL-7RĪ±. It forms a heterodimer with the common Ī³ chain (Ī³c or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development. |
 | C57BL/6 murine splenocytes are stained with Anti-Mouse CD127 Monoclonal Antibody(PE Conjugated)(filled gray histogram). Unstained splenocytes (empty black histogram) are used as control. |
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