Description
Antibody Name: | Mouse CD11c Monoclonal Antibody (PE Conjugated) |
Antibody Code: | AGEL0514 |
Size: | 50µg |
Clone: | N418 |
Synonyms: | Integrin alpha-X,Itgax,CD11 antigen-like family member C,Leukocyte adhesion receptor p150+95,CD11c |
Host Species: | Armenian Hamster |
Species Reactivity: | Mouse |
Applications: | FC |
Concentration: | 1mg/mL |
Isotype: | IgG2a,k |
Conjugation: | PE |
Applications: | FC |
Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Storage Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. |
Gene ID: | 16411 |
Uniprot: | Q9QXH4 |
Background: | CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54. |
C57BL/6 murine splenocytes are stained with Anti-Mouse CD11c Monoclonal Antibody(PE Conjugated) and Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody(APC Conjugated)[Both antibodies are used at 0.02 ?g/106 cells dilution]. Splenocytes stained with Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody(APC Conjugated)(Right) are used as control |