Mouse CD11c Monoclonal Antibody (AF647 Conjugated) [N418](AGEL0522)

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SKU:
AGEL0522
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
IgG2a,k
Clone:
N418
Conjugation:
AF 647

Description

Antibody Name:Mouse CD11c Monoclonal Antibody (AF647 Conjugated)
Antibody Code:AGEL0522
Size:50µg
Clone:N418
Synonyms:Integrin alpha-X,Itgax,CD11 antigen-like family member C,Leukocyte adhesion receptor p150+95,CD11c
Host Species:Armenian Hamster
Species Reactivity:Mouse
Applications:FC
Concentration:1mg/mL
Isotype:IgG2a,k
Conjugation:AF647
Applications:FC
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:PBS with 0.05% Proclin300, 1% BSA
Storage:Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.
Gene ID:16411
Uniprot:Q9QXH4
Background:CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.
Mouse CD19 Monoclonal Antibody (FITC Conjugated)C57BL/6 murine splenocytes are stained with Anti-Mouse CD11c Monoclonal Antibody(AF647 Conjugated) and Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody(FITC Conjugated)[Both antibodies are used at 0.2 ?g/106 cells dilution]. Splenocytes stained with Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody(FITC Conjugated)(right) are used as control.
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