Immune Checkpoint Recombinant Proteins

Mouse BTLA Recombinant Protein (His Tag) (HDPT0176)

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SKU:: HDPT0176
UPC:
MPN:
Product Type:: Recombinant Protein
Species:: Mouse
Research Area:: Immune Checkpoint

Description
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Description

Mouse BTLA Recombinant Protein (His Tag)

Description:	Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006). May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14 (PubMed:19915044). In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells (PubMed:19915044).
Product name:	Mouse BTLA Recombinant Protein (His Tag)
Synonyms:	BTLA,CD272
Type:	protein
Size:	50 µg
Name:	Mouse BTLA
Origin:	Mouse
Source:	HEK293
Protein Type:	Recombinant
Application:	Contact Technical Support
Purity:	> 95%
Purification:	affinity purification
Format:	Lyophilized
Conjugate:	C-6×His tag
Storage:	Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:	Research use only
Buffer:	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:	Reconstitute with deionized water
Sequence:	Mouse BTLA（Glu30-Pro176) +6×His tag
Gene ID:	208154
Uniprot:	Q7TSA3
Molecular Weight:	35-55 kDa