Immune Checkpoint Recombinant Proteins

Mouse BTLA Recombinant Protein (His Tag) (HDPT0176)

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SKU:
HDPT0176
Product Type:
Recombinant Protein
Species:
Mouse
Research Area:
Immune Checkpoint

Description

Mouse BTLA Recombinant Protein (His Tag)

Description:Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006). May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14 (PubMed:19915044). In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells (PubMed:19915044).
Product name:Mouse BTLA Recombinant Protein (His Tag)
Synonyms:BTLA,CD272
Type:protein
Size:50 µg
Name:Mouse BTLA
Origin:Mouse
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:> 95%
Purification:affinity purification
Format:Lyophilized
Conjugate:C-6×His tag
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence: Mouse BTLA(Glu30-Pro176) +6×His tag
Gene ID:208154
Uniprot:Q7TSA3
Molecular Weight:35-55 kDa
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