Mouse Biglycan/BGN Recombinant Protein (RPES4649)

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SKU:
RPES4649
Product Type:
Recombinant Protein
Species:
Mouse

Description

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Mouse Biglycan/BGN Recombinant Protein

Biglycan, also known as PG-S1 and BGN, is a a small leucine-rich repeat proteoglycan (SLRP). It can be detected in a variety of extracellular matrix tissues, including bone, cartilage and tendon. Biglycan consists of a protein core containing leucine-rich repeat regions and two glycosaminoglycan (GAG) chains consisting of either chondroitin sulfate (CS) or dermatan sulfate (DS). Non-glycanated forms of biglycan (no GAG chains) increase with age in human articular cartilage. Biglycan interacts with collagen, both via the core protein and GAG chains. Biglycan plays a role in the mineralisation of bone. Biglycan core protein binds to the growth factors BMP-4 and influences its bioactivity.

Product Name:Mouse Biglycan/BGN Recombinant Protein (RPES4649)
Product Code:RPES4649
Size:50µg
Species:Mouse
Expressed Host:HEK293 Cells
Synonyms:BG,DSPG1,PG-S1,PGI,SLRR1A
Accession:NP_031568.2
Sequence:Met1-Lys369
Fusion tag:C-Fc
Endotoxin:<1.0 EU per µg of the protein as determined by the LAL method.
Protein Construction:A DNA sequence encoding the mouse BGN (Met1-Lys369) was expressed with the Fc region of human IgG1 at the C-terminus.
Purity:> 85 % as determined by SDS-PAGE
Mol Mass:66.5 kDa
AP Mol Mass:67 kDa
Formulation:Lyophilized from sterile PBS, pH 7.4
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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