Cytokines Recombinant Proteins

Mouse BD 3 Recombinant Protein (RPPB0074)

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RPPB0074

Description

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Product Name:Mouse BD 3 Recombinant Protein
Product Code:RPPB0074
Size:20µg
Species:Mouse
Target:BD 3
Synonyms:Beta-defensin 3, BD-3, mBD-3, Defensin beta 3, Defb3, Bd3, MGC129397.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation:The Mouse BD-3 was lyophilized from a 0.2�m filtered concentrated solution in PBS, pH7.4.
Solubility:It is recommended to reconstitute the lyophilized Beta Defensin-3 in sterile 18M-cm H2O not less than 100�g/ml, which can then be further diluted to other aqueous solutions.
Stability:Lyophilized Beta Defensin-3 Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BD-3 should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles.
Purity:Greater than 98.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Amino Acid Sequence:KKINNPVSCL RKGGRCWNRC IGNTRQIGSC GVPFLKCCKR K
Biological Activity:Measured by its antimicrobial activity against E. coli. The ED50 for this effect is typically 4-20�g/ml, corresponding to a specific activity of 50,000-250,000units/mg.

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103A, which has broad spectrum antimicrobial activity and may play an important role in innate epithelial defense.

Beta Defensin-3 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 41 amino acids and having a molecular mass of 4.6kDa. The BD-3 is purified by proprietary chromatographic techniques.

UniProt Protein Function:Antimicrobial activity against Gram-negative bacteria E.coli and P.aeruginosa.
UniProt Code:Q9WTL0
NCBI GenInfo Identifier:18203569
NCBI Gene ID:27358
NCBI Accession:Q9WTL0.1
UniProt Secondary Accession:Q9WTL0,Q29R78,
UniProt Related Accession:Q9WTL0
Molecular Weight:5.1 kDa
NCBI Full Name:Beta-defensin 3
NCBI Synonym Full Names:defensin beta 3
NCBI Official Symbol:Defb3��
NCBI Official Synonym Symbols:BD-3��
NCBI Protein Information:beta-defensin 3
UniProt Protein Name:Beta-defensin 3
UniProt Synonym Protein Names:Defensin, beta 3
UniProt Gene Name:Defb3��
UniProt Entry Name:DEFB3_MOUSE
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Additional Information

Product Type:
Recombinant Protein
Species:
Mouse
Uniprot:
Q9WTL0
Research Area:
Cytokines
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