Mouse APCS/SAP Recombinant Protein (RPES0516)
- SKU:
- RPES0516
- Product Type:
- Recombinant Protein
- Species:
- Mouse
Description
system_update_altDatasheet
Mouse APCS/SAP Recombinant Protein
Pentraxin 2 (PTX2), also known as Serum amyloid P (SAP), is a highly conserved, naturally circulating plasma protein and a soluble pattern recognition receptor of the innate immune system. The unique binding activities indicated that it may play an important role in the removal of damaged tissue. PTX2 belongs to the pentraxin family, is universally present in amyloid deposits. Mouse with targeted deletion of the PTX2 gene shows retarded and reduced induction of experimental reactive systemic (AA type) amyloidosis confirmed that it does indeed contribute to pathogenesis of amyloidosis and is a valid therapeutic target. In recent discovery, PTX2 can be used as a powerful antifibrotic agent to regulate certain monocyte differentiation states.
| Product Name: | Mouse APCS/SAP Recombinant Protein (RPES0516) |
| Product Code: | RPES0516 |
| Size: | 10µg |
| Species: | Mouse |
| Expressed Host: | Human Cells |
| Synonyms: | APCS, PTX2, SAP, 9.5S alpha-1-glycoprotein, Serum amyloid P, MGC88159, PTX2serum amyloid P-component, SAP pentaxin-related |
| Accession: | NP_035448.2 |
| Sequence: | Gln21-Asp224 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Mouse Serum Amyloid P Component is produced by our Mammalian expression system and the target gene encoding Gln21-Asp224 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by SDS-PAGE |
| Mol Mass: | 24.9 kDa |
| AP Mol Mass: | 28-32 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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