Mouse 4BB/TNFRSF9 Recombinant Protein (RPES4893)
- SKU:
- RPES4893
- Product Type:
- Recombinant Protein
- Species:
- Mouse
Description
system_update_altDatasheet
Mouse 4BB/TNFRSF9 Recombinant Protein
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, TNFRSF9 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. As receptor for TNFSF9/4-1BBL, it can activate T cells and the cross-linking of this protein can enhance T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.
| Product Name: | Mouse 4BB/TNFRSF9 Recombinant Protein (RPES4893) |
| Product Code: | RPES4893 |
| Size: | 10µg |
| Species: | Mouse |
| Expressed Host: | Human Cells |
| Synonyms: | 4-1BB, A930040I11Rik, AA408498, AI325004, Cd137, CDw137, ILA, Ly63,Secreted CD137 antigen ,Tumor necrosis factor receptor superfamily member 9 ,Tnfrsf9 |
| Accession: | NP_001070976.1 |
| Sequence: | Val24-Leu187 |
| Fusion tag: | C-Fc |
| Activity: | Immobilized Human 4-1BBL-His(Cat: PKSH032023) at 0.05µg/ml(100 ?l/well) can bind Mouse 4-1BB-Fc. |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Mouse 4-1BB ligand receptor is produced by our Mammalian expression system and the target gene encoding Val24-Leu187 is expressed with a Fc tag at the C-terminus. |
| Purity: | > 95 % as determined by SDS-PAGE |
| Mol Mass: | 44.7 kDa |
| AP Mol Mass: | 60-70 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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