MND1 Antibody (PACO41550)
- SKU:
- PACO41550
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MND1 Antibody (PACO41550) |
| Antibody SKU: | PACO41550 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Meiotic nuclear division protein 1 homolog protein (2-205AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: MND1 antibody at 10µg/ml + Jurkat whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 24 kDa. Observed band size: 24 kDa. |
 | Immunohistochemistry of paraffin-embedded human endometrial cancer using PACO41550 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human gastric cancer using PACO41550 at dilution of 1:100. |
| Background: | Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Stimulates both DMC1- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks. |
| Synonyms: | Meiotic nuclear division protein 1 homolog, MND1, GAJ |
| UniProt Protein Function: | MND1: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Stimulates both DMC1- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks. Belongs to the MND1 family. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 4q31.3 Cellular Component: nucleus Molecular Function:DNA binding Biological Process: meiotic cell cycle; DNA recombination |
| NCBI Summary: | The product of the MND1 gene associates with HOP2 (MIM 608665) to form a stable heterodimeric complex that binds DNA and stimulates the recombinase activity of RAD51 (MIM 179617) and DMC1 (MIM 602721) (Chi et al., 2007 [PubMed 17639080]). Both the MND1 and HOP2 genes are indispensable for meiotic recombination.[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9BWT6 |
| NCBI GenInfo Identifier: | 74733462 |
| NCBI Gene ID: | 84057 |
| NCBI Accession: | Q9BWT6.1 |
| UniProt Secondary Accession: | Q9BWT6,B2R5F9, |
| UniProt Related Accession: | Q9BWT6 |
| Molecular Weight: | 205 |
| NCBI Full Name: | Meiotic nuclear division protein 1 homolog |
| NCBI Synonym Full Names: | meiotic nuclear divisions 1 homolog (S. cerevisiae) |
| NCBI Official Symbol: | MND1 |
| NCBI Official Synonym Symbols: | GAJ |
| NCBI Protein Information: | meiotic nuclear division protein 1 homolog; MND1; homolog of yeast MND1 |
| UniProt Protein Name: | Meiotic nuclear division protein 1 homolog |
| Protein Family: | MND1-interacting protein |
| UniProt Gene Name: | MND1 |
| UniProt Entry Name: | MND1_HUMAN |
| Antibodies |
| MND1 Antibody (PACO10533) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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