Description
Antibody Name: | MND1 Antibody (PACO10533) |
Antibody SKU: | PACO10533 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse |
Immunogen: | Human MND1 |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | meiotic nuclear divisions 1 homolog (S. cerevisiae);MND1;GAJ ; |
UniProt Protein Function: | MND1: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Stimulates both DMC1- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks. Belongs to the MND1 family. |
UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 4q31.3 Cellular Component: nucleus Molecular Function:DNA binding Biological Process: meiotic cell cycle; DNA recombination |
NCBI Summary: | The product of the MND1 gene associates with HOP2 (MIM 608665) to form a stable heterodimeric complex that binds DNA and stimulates the recombinase activity of RAD51 (MIM 179617) and DMC1 (MIM 602721) (Chi et al., 2007 [PubMed 17639080]). Both the MND1 and HOP2 genes are indispensable for meiotic recombination.[supplied by OMIM, Mar 2008] |
UniProt Code: | Q9BWT6 |
NCBI GenInfo Identifier: | 74733462 |
NCBI Gene ID: | 84057 |
NCBI Accession: | Q9BWT6.1 |
UniProt Secondary Accession: | Q9BWT6,B2R5F9, |
UniProt Related Accession: | Q9BWT6 |
Molecular Weight: | 205 |
NCBI Full Name: | Meiotic nuclear division protein 1 homolog |
NCBI Synonym Full Names: | meiotic nuclear divisions 1 homolog (S. cerevisiae) |
NCBI Official Symbol: | MND1 |
NCBI Official Synonym Symbols: | GAJ |
NCBI Protein Information: | meiotic nuclear division protein 1 homolog; MND1; homolog of yeast MND1 |
UniProt Protein Name: | Meiotic nuclear division protein 1 homolog |
Protein Family: | MND1-interacting protein |
UniProt Gene Name: | MND1 |
UniProt Entry Name: | MND1_HUMAN |