MMP9 Monoclonal Antibody
- SKU:
- CAB23535
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | MMP9 Monoclonal Antibody |
| Product Code: | CAB23535 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC60372 |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T-MMP9 |
| Cellular Location: | Secreted, extracellular matrix, extracellular space |
| Customer Validation: | WB(Rattus norvegicus) |
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-707 of human MMP9 (NP_004985.2). |
| Sequence: | APRQR QSTLV LFPGD LRTNL TDRQL AEEYL YRYGY TRVAE MRGES KSLGP ALLLL QKQLS LPETG ELDSA TLKAM RTPRC GVPDL GRFQT FEGDL KWHHH NITYW IQNYS EDLPR AVIDD AFARA FALWS AVTPL TFTRV YSRDA DIVIQ FGVAE HGDGY PFDGK DGLLA HAFPP GPGIQ GDAHF DDDEL WSLGK GVVVP TRFGN ADGAA CHFPF IFEGR SYSAC TTDGR SDGLP WCSTT ANYDT DDRFG FCPSE RLYTQ DGNAD GKPCQ FPFIF QGQSY SACTT DGRSD GYRWC ATTAN YDRDK LFGFC PTRAD STVMG GNSAG ELCVF PFTFL GKEYS TCTSE GRGDG RLWCA TTSNF DSDKK WGFCP DQGYS LFLVA AHEFG HALGL DHSSV PEALM YPMYR FTEGP PLHKD DVNGI RHLYG PRPEP EPRPP TTTTP QPTAP PTVCP TGPPT VHPSE RPTAG PTGPP SAGPT GPPTA GPSTA TTVPL SPVDD ACNVN IFDAI AEIGN QLYLF KDGKY WRFSE GRGSR PQGPF LIADK WPALP RKLDS VFEER LSKKL FFFSG RQVWV YTGAS VLGPR RLDKL GLGAD VAQVT GALRS GRGKM LLFSG RRLWR FDVKA QMVDP RSASE VDRMF PGVPL DTHDV FQYRE KAYFC QDRFY WRVSS RSELN QVDQV GYVTY DILQC PED |
| Synonyms: | GELB, CLG4B, MMP-9, MANDP2 |
| Calculated MW: | 78kDa |
| Observed MW: | 100kDa |
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