MMP21 Antibody (PACO18230)
- SKU:
- PACO18230
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MMP21 Antibody (PACO18230) |
| Antibody SKU: | PACO18230 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human MMP21 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18230(MMP21 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO18230(MMP21 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This gene encodes a member of the matrix metalloproteinase family. Proteins in this family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction, and tissue remodeling,and disease processes, such as asthma and metastasis. The encoded protein may play an important role in embryogenesis, particularly in neuronal cells, as well as in lymphocyte development and survival. |
| Synonyms: | matrix metallopeptidase 21 |
| UniProt Protein Function: | MMP21: May have an important and specific function in tumor progression and embryogenesis. Cleaves alpha-1-antitrypsin. Belongs to the peptidase M10A family.Protein type: EC 3.4.24.-; Secreted, signal peptide; Secreted; ProteaseChromosomal Location of Human Ortholog: 10q26.13Cellular Component: extracellular matrix; extracellular regionMolecular Function: zinc ion binding; metalloendopeptidase activity; calcium ion bindingBiological Process: hemopoietic progenitor cell differentiation; proteolysis |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the matrix metalloproteinase family. Proteins in this family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, and disease processes, such as asthma and tumor metastasis. The encoded protein may play an important role in embryogenesis, particularly in neuronal cells, as well as in lymphocyte development and survival. [provided by RefSeq, May 2013] |
| UniProt Code: | Q8N119 |
| NCBI GenInfo Identifier: | 22218341 |
| NCBI Gene ID: | 118856 |
| NCBI Accession: | NP_671724.1 |
| UniProt Secondary Accession: | Q8N119,Q5VZP9, Q8NG02 |
| UniProt Related Accession: | Q8N119 |
| Molecular Weight: | 65,043 Da |
| NCBI Full Name: | matrix metalloproteinase-21 preproprotein |
| NCBI Synonym Full Names: | matrix metallopeptidase 21 |
| NCBI Official Symbol: | MMP21 |
| NCBI Official Synonym Symbols: | MMP-21 |
| NCBI Protein Information: | matrix metalloproteinase-21 |
| UniProt Protein Name: | Matrix metalloproteinase-21 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Matrix metallopeptidase |
| UniProt Gene Name: | MMP21 |
| UniProt Entry Name: | MMP21_HUMAN |
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