Name: MMD2 Antibody (PACO37794)
SKU: PACO37794
Availability: OutOfStock

Antibody Name:	MMD2 Antibody (PACO37794)
Antibody SKU:	PACO37794
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC, IF
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200
Species Reactivity:	Human, Mouse
Immunogen:	Recombinant Human Monocyte to macrophage differentiation factor 2 protein (1-38AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Western blot. All lanes: MMD2 antibody at 3µg/ml. Lane 1: Mouse brain tissue. Lane 2: Mouse kidney tissue. Lane 3: U251 whole cell lysate. Lane 4: 293T whole cell lysate. Lane 5: Mouse liver tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 32, 29, 23 kDa. Observed band size: 23 kDa.
	Immunofluorescent analysis of U251 cells using PACO37794 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
	Immunohistochemistry of paraffin-embedded human testis tissue using PACO37794 at dilution of 1:100.

Background:	perinuclear region of cytoplasm, protein kinase activity, positive regulation of neuron differentiation, positive regulation of protein kinase activity, positive regulation of Ras protein signal transduction, protein phosphorylation, regulation of protein localization
Synonyms:	Monocyte to macrophage differentiation factor 2 (Progestin and adipoQ receptor family member 10) (Progestin and adipoQ receptor family member X), MMD2, PAQR10

UniProt Protein Function:	MMD2: a member of the PAQR (progestin and adipoQ receptor) family. Members of this family are evolutionarily conserved with significant sequence identity to bacterial hemolysin-like proteins and are defined by a set of seven transmembrane domains. The protein encoded by this gene localizes to the Golgi apparatus to modulate Ras signaling. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jun 2012]Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 7p22.1Cellular Component: perinuclear region of cytoplasmMolecular Function: protein kinase activityBiological Process: positive regulation of neuron differentiation; positive regulation of protein kinase activity; positive regulation of Ras protein signal transduction; regulation of protein localization
UniProt Protein Details:
NCBI Summary:	This gene encodes a member of the PAQR (progestin and adipoQ receptor) family. Members of this family are evolutionarily conserved with significant sequence identity to bacterial hemolysin-like proteins and are defined by a set of seven transmembrane domains. The protein encoded by this gene localizes to the Golgi apparatus to modulate Ras signaling. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jun 2012]
UniProt Code:	Q8IY49
NCBI GenInfo Identifier:	51701810
NCBI Gene ID:	221938
NCBI Accession:	Q8IY49.2
UniProt Secondary Accession:	Q8IY49,Q6NVU5, Q6TCH0, B5MBW4
UniProt Related Accession:	Q8IY49
Molecular Weight:	22,730 Da
NCBI Full Name:	Monocyte to macrophage differentiation factor 2
NCBI Synonym Full Names:	monocyte to macrophage differentiation associated 2
NCBI Official Symbol:	MMD2
NCBI Official Synonym Symbols:	PAQR10
NCBI Protein Information:	monocyte to macrophage differentiation factor 2
UniProt Protein Name:	Monocyte to macrophage differentiation factor 2
UniProt Synonym Protein Names:	Progestin and adipoQ receptor family member 10; Progestin and adipoQ receptor family member X
Protein Family:	Monocyte to macrophage differentiation factor
UniProt Gene Name:	MMD2
UniProt Entry Name:	PAQRA_HUMAN