MITF Monoclonal Antibody
- SKU:
- CAB22091
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | MITF Monoclonal Antibody |
| Product Code: | CAB22091 |
| Reactivity: | Human, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC55801 |
| Reactivity: | Human, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:2000-1:20000, IF/ICC 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, Rat heart |
| Cellular Location: | Nucleus, Cytoplasm |
The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 402-526 of human MITF (NP_001341533.1). |
| Sequence: | HGLSL IPSTG LCSPD LVNRI IKQEP VLENC SQDLL QHHAD LTCTT TLDLT DGTIT FNNNL GTGTE ANQAY SVPTK MGSKL EDILM DDTLS PVGVT DPLLS SVSPG ASKTS SRRSS MSMEE TEHTC |
| Synonyms: | MI, WS2, CMM8, WS2A, COMMAD, MITF-A, bHLHe32 |
| Calculated MW: | 59kDa |
| Observed MW: | 50-75kDa |
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