MIP 1a Monoclonal Antibody [YNR-HMIP1a] (CPAB0001)

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SKU:
CPAB0001
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
YNR-HMIP1a
Applications:
IP
Applications:
WB
Applications:
ELISA

Description

system_update_alt Datasheet
Product Name:MIP 1a Antibody
Product Sku:CPAB0001
Size:500μg
Host Species:Mouse
Immunogen:r.Human MIP1-a
Clone:YNR-HMIP1a.
Reactivity:Human
Applications:Immuneprecipitation, Western Blot, ELISA
Purification Method:Ion exchange
Isotype:IgG1
Background:Macrophage Inflammatory Proteins (MIP) belong to the family of chemotactic cytokines known as chemokines. In humans, there are two major forms, MIP-1a and MIP-1b that are now officially named CCL3 and CCL4 respectively. Both are major factors produced by macrophages after they are stimulated with bacterial endotoxins. They activate human granulocytes (neutrophils, eosinophilsand basophils) which can lead to acute neutrophilic inflammation. They also induce the synthesis and release of other pro-inflammatory cytokines such as interleukin 1(IL-1), IL-6 and TNF-a from fibroblasts and macrophages. The genes for CCL3 and CCL4 are both located on human chromosome 17.
Synonyms:Worked Small inducible cytokine A3, CCL3, Macrophage inflammatory protein 1-alpha, MIP-1-alpha, Tonsillar lymphocyte LD78 alpha protein, G0/G1 switch regulatory protein 19-1, G0S19-1 protein, SIS-beta, PAT 464.1, chemokine (C-C motif) ligand 3, MIP1A, SCYA3, G0S19-1, LD78ALPHA.
Storage Buffer:In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.
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