Minpp1 Antibody (PACO28246)
- SKU:
- PACO28246
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Minpp1 Antibody (PACO28246) |
| Antibody SKU: | PACO28246 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Rat |
| Immunogen: | Recombinant Rat Multiple inositol polyphosphate phosphatase 1 protein (31-481AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification). |
| Synonyms: | Multiple inositol polyphosphate phosphatase 1 (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase), Minpp1, Mipp1 |
| UniProt Protein Function: | Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification). May play a role in the transition of chondrocytes from proliferation to hypertrophy (). |
| UniProt Protein Details: | |
| NCBI Summary: | catalyzes the hydrolysis of Ins(1,3,4,5,6)P5, first to Ins(1,4,5,6)P4 and then to Ins(1,4,5)P3, by consecutive 3- and 6-phosphatase activities [RGD, Feb 2006] |
| UniProt Code: | O35217 |
| NCBI GenInfo Identifier: | 158749647 |
| NCBI Gene ID: | 29688 |
| NCBI Accession: | NP_062136.1 |
| UniProt Secondary Accession: | O35217 |
| UniProt Related Accession: | O35217 |
| Molecular Weight: | 53.59kD |
| NCBI Full Name: | multiple inositol polyphosphate phosphatase 1 |
| NCBI Synonym Full Names: | multiple inositol-polyphosphate phosphatase 1 |
| NCBI Official Symbol: | Minpp1 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | multiple inositol polyphosphate phosphatase 1 |
| UniProt Protein Name: | Multiple inositol polyphosphate phosphatase 1 |
| UniProt Synonym Protein Names: | 2,3-bisphosphoglycerate 3-phosphatase (EC:3.1.3.80); 2,3-BPG phosphatase; Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase; Ins(1,3,4,5)P(4) 3-phosphatase |
| Protein Family: | Multiple inositol polyphosphate phosphatase |
| UniProt Gene Name: | Minpp1 |
| UniProt Entry Name: |
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