MILR1 Antibody (PACO46742)
- SKU:
- PACO46742
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MILR1 Antibody (PACO46742) |
| Antibody SKU: | PACO46742 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Allergin-1 protein (249-343AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: MILR1 antibody at 14 µg/ml. Lane 1: Mouse brain tissue. Lane 2: HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 39, 28, 29 kDa. Observed band size: 39, 120 kDa.. |
 | Immunofluorescent analysis of HepG2 cells using PACO46742 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human liver cancer using PACO46742 at dilution of 1:100. |
| Background: | Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction (By similarity). |
| Synonyms: | Allergin-1 (Allergy inhibitory receptor 1) (Mast cell antigen 32) (MCA-32) (Mast cell immunoglobulin-like receptor 1), MILR1, C17orf60 MCA32 |
| UniProt Protein Function: | MCA32: Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE- mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 17q23.3Biological Process: mast cell degranulation; negative regulation of mast cell activation |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q7Z6M3 |
| NCBI GenInfo Identifier: | 146229333 |
| NCBI Gene ID: | 284021 |
| NCBI Accession: | NP_001078892.1 |
| UniProt Secondary Accession: | Q7Z6M3,A1L458, B4DUS1, B7ZM50, B9EGN0, D6RUW6, D6RUW8 |
| UniProt Related Accession: | Q7Z6M3 |
| Molecular Weight: | 28,656 Da |
| NCBI Full Name: | allergin-1 isoform Allergin-1L |
| NCBI Synonym Full Names: | mast cell immunoglobulin like receptor 1 |
| NCBI Official Symbol: | MILR1 |
| NCBI Official Synonym Symbols: | MCA32; MCA-32; C17orf60; Allergin-1 |
| NCBI Protein Information: | allergin-1 |
| UniProt Protein Name: | Allergin-1 |
| UniProt Synonym Protein Names: | Allergy inhibitory receptor 1; Mast cell antigen 32; MCA-32; Mast cell immunoglobulin-like receptor 1 |
| Protein Family: | Allergin |
| UniProt Gene Name: | MILR1 |
| UniProt Entry Name: | MILR1_HUMAN |
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