Description
Antibody Name: | MIG7 Antibody (PACO20021) |
Antibody SKU: | PACO20021 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human MIG7 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20021(MIG7 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | Gel: 12%SDS-PAGE, Lysate: 40 µg, Lane 1-2: Human placenta tissue, Human breast infiltrative duct tissue, Primary antibody: PACO20021(MIG7 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO20021(MIG7 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | MIG-7 protein inhibited protein phosphatase 2A to sustain Akt/GSK-3 β phosphorylation and cancer-cell migration/invasion. Cancer cells overexpressing MIG-7 exhibited increased expression of ZEB-1 and Twist in parallel with epithelial-mesenchymal transition, metastasis and cancer lethality. MIG-7 protein level positively correlated with advanced stages of human lung cancers. |
Synonyms: | mig-7 |
UniProt Protein Function: | MIG7: Chromosomal Location of Human Ortholog: 1p22.1 |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q1AHR6 |
NCBI GenInfo Identifier: | 102863546 |
NCBI Gene ID: | |
NCBI Accession: | ABF71424.1 |
UniProt Secondary Accession: | Q1AHR6 |
UniProt Related Accession: | Q1AHR6 |
Molecular Weight: | 35.3kDa |
NCBI Full Name: | MIG7 |
NCBI Synonym Full Names: | |
NCBI Official Symbol: | |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | |
UniProt Protein Name: | MIG7 |
UniProt Synonym Protein Names: | MIG7 |
Protein Family: | |
UniProt Gene Name: | MIG7 |
UniProt Entry Name: | Q1AHR6_HUMAN |