MIG7 Antibody (PACO20021)
- SKU:
- PACO20021
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MIG7 Antibody (PACO20021) |
| Antibody SKU: | PACO20021 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human MIG7 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20021(MIG7 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | Gel: 12%SDS-PAGE, Lysate: 40 µg, Lane 1-2: Human placenta tissue, Human breast infiltrative duct tissue, Primary antibody: PACO20021(MIG7 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO20021(MIG7 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | MIG-7 protein inhibited protein phosphatase 2A to sustain Akt/GSK-3 β phosphorylation and cancer-cell migration/invasion. Cancer cells overexpressing MIG-7 exhibited increased expression of ZEB-1 and Twist in parallel with epithelial-mesenchymal transition, metastasis and cancer lethality. MIG-7 protein level positively correlated with advanced stages of human lung cancers. |
| Synonyms: | mig-7 |
| UniProt Protein Function: | MIG7: Chromosomal Location of Human Ortholog: 1p22.1 |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q1AHR6 |
| NCBI GenInfo Identifier: | 102863546 |
| NCBI Gene ID: | |
| NCBI Accession: | ABF71424.1 |
| UniProt Secondary Accession: | Q1AHR6 |
| UniProt Related Accession: | Q1AHR6 |
| Molecular Weight: | 35.3kDa |
| NCBI Full Name: | MIG7 |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | MIG7 |
| UniProt Synonym Protein Names: | MIG7 |
| Protein Family: | |
| UniProt Gene Name: | MIG7 |
| UniProt Entry Name: | Q1AHR6_HUMAN |
Related Products
SIM1 Antibody
Overview Product Name:SIM1 AntibodyProduct Code:PACO64949Size:50µLTarget Names:SIM1Species Reactivity:HumanHost
eutC Antibody
Overview Product Name:eutC AntibodyProduct Code:PACO64709Size:50µLTarget Names:eutCSpecies Reactivity:Escherichia coli
EPHA10 Antibody
Overview Product Name:EPHA10 AntibodyProduct Code:PACO64693Size:50µLTarget Names:EPHA10Species Reactivity:HumanH
otsB Antibody
Overview Product Name:otsB AntibodyProduct Code:PACO64885Size:50µLTarget Names:otsBSpecies Reactivity:Escherichia coli