MIG7 Antibody (PACO20020)
- SKU:
- PACO20020
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MIG7 Antibody (PACO20020) |
| Antibody SKU: | PACO20020 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human MIG7 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO20020(MIG7 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | Gel: 12%SDS-PAGE, Lysate: 40 µg, Lane 1-2: Human breast infiltrative duct tissue, Human placenta tissue, Primary antibody: PACO20020(MIG7 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO20020(MIG7 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | MIG-7 protein inhibited protein phosphatase 2A to sustain Akt/GSK-3 β phosphorylation and cancer-cell migration/invasion. Cancer cells overexpressing MIG-7 exhibited increased expression of ZEB-1 and Twist in parallel with epithelial-mesenchymal transition, metastasis and cancer lethality. MIG-7 protein level positively correlated with advanced stages of human lung cancers. |
| Synonyms: | mig-7 |
| UniProt Protein Function: | MIG7: Chromosomal Location of Human Ortholog: 1p22.1 |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q1AHR6 |
| NCBI GenInfo Identifier: | 102863546 |
| NCBI Gene ID: | |
| NCBI Accession: | ABF71424.1 |
| UniProt Secondary Accession: | Q1AHR6 |
| UniProt Related Accession: | Q1AHR6 |
| Molecular Weight: | 35.3kDa |
| NCBI Full Name: | MIG7 |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | MIG7 |
| UniProt Synonym Protein Names: | MIG7 |
| Protein Family: | |
| UniProt Gene Name: | MIG7 |
| UniProt Entry Name: | Q1AHR6_HUMAN |
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