Description
| Product Name: | MIF Polyclonal Antibody |
| Product Code: | CAB22014 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, HL-60, Mouse brain, Mouse thymus, Rat brain, Rat testis |
| Cellular Location: | cell surface, cytoplasm, cytosol, extracellular exosome, extracellular region, extracellular space, nucleoplasm, plasma membrane |
This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 2-115 of human MIF (NP_002406.1). |
| Sequence: | PMFIV NTNVP RASVP DGFLS ELTQQ LAQAT GKPPQ YIAVH VVPDQ LMAFG GSSEP CALCS LHSIG KIGGA QNRSY SKLLC GLLAE RLRIS PDRVY INYYD MNAAN VGWNN STFA |
| Synonyms: | GIF, GLIF, MMIF |
| Calculated MW: | 12kDa |
| Observed MW: | 12kDa |