Antibody Name:	Mif Antibody?FITC conjugated (PACO64045)
Antibody SKU:	PACO64045
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA
Recommended Dilutions:
Species Reactivity:	Mouse
Immunogen:	Recombinant Mouse Macrophage migration inhibitory factor protein (2-115AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:	>95%, Antigen Affinity purified & Affinity purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	FITC

Background:

Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity (By similarity).

Synonyms:

Macrophage migration inhibitory factor (MIF) (EC 5.3.2.1) (Delayed early response protein 6) (DER6) (Glycosylation-inhibiting factor) (GIF) (L-dopachrome isomerase) (L-dopachrome tautomerase) (EC 5.3.3.12) (Phenylpyruvate tautomerase), Mif

UniProt Protein Function:	Function: Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity
UniProt Protein Details:	Catalytic activity: Keto-phenylpyruvate = enol-phenylpyruvate.1 PublicationManual assertion based on experiment in:Ref.12
UniProt Code:	P34884
NCBI GenInfo Identifier:	6754696
NCBI Gene ID:	17319
NCBI Accession:	NP_034928.1
UniProt Related Accession:	P34884
Molecular Weight:	12,504 Da
NCBI Full Name:	macrophage migration inhibitory factor
NCBI Synonym Full Names:	macrophage migration inhibitory factor
NCBI Official Symbol:	Mif
NCBI Official Synonym Symbols:	GIF; Glif
NCBI Protein Information:	macrophage migration inhibitory factor; DER6; L-dopachrome isomerase; L-dopachrome tautomerase; phenylpyruvate tautomerase; glycosylation-inhibiting factor; delayed early response protein 6
UniProt Protein Name:	Macrophage migration inhibitory factor
UniProt Synonym Protein Names:	Delayed early response protein 6; DER6; Glycosylation-inhibiting factor; GIF; L-dopachrome isomerase; L-dopachrome tautomerase (EC:5.3.3.12); Phenylpyruvate tautomerase
Protein Family:	Macrophage migration inhibitory factor
UniProt Gene Name:	Mif
UniProt Entry Name:	MIF_MOUSE