MIDN Antibody (PACO18224)
- SKU:
- PACO18224
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MIDN Antibody (PACO18224) |
| Antibody SKU: | PACO18224 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:1000-1:5000, WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human MIDN |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human lung tissue, Primary antibody: PACO18224(MIDN Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes. |
| Background: | Expression of the midnolin gene is developmentally regulated: it is strongly expressed at the mesencephalon (midbrain) of the embryo in day 12.5 (E12.5) mice. The midnolin encodes a protein of 508 amino acid, (aa), which contains a Ubiquitin-like domain. The intracellular distribution of the midnolin was studied by using midnolin-green fluorescent protein (GFP) fusion proteins. Midnolin was found to be localized in the nucleus and nucleolus, but not in the cytoplasm. The nucleolar localization signal was determined to be a 28aa peptide located at the C-terminal region of the midnolin. May be involved in regulation of genes related to neurogenesis in the nucleolus |
| Synonyms: | Midnolin |
| UniProt Protein Function: | MIDN: May be involved in regulation of genes related to neurogenesis in the nucleolus. |
| UniProt Protein Details: | Protein type:Nucleolus Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: nucleolus; cytosol Molecular Function:kinase binding Biological Process: negative regulation of glucokinase activity; negative regulation of insulin secretion |
| UniProt Code: | Q504T8 |
| NCBI GenInfo Identifier: | 296437369 |
| NCBI Gene ID: | 90007 |
| NCBI Accession: | Q504T8.2 |
| UniProt Related Accession: | Q504T8 |
| Molecular Weight: | |
| NCBI Full Name: | Midnolin |
| NCBI Synonym Full Names: | midnolin |
| NCBI Official Symbol: | MIDN |
| NCBI Protein Information: | midnolin |
| UniProt Protein Name: | Midnolin |
| UniProt Synonym Protein Names: | Midbrain nucleolar protein |
| Protein Family: | Midnolin |
| UniProt Gene Name: | MIDN |
| UniProt Entry Name: | MIDN_HUMAN |
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