Description
Antibody Name: | MIDN Antibody (PACO18224) |
Antibody SKU: | PACO18224 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:1000-1:5000, WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human MIDN |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human lung tissue, Primary antibody: PACO18224(MIDN Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes. |
Background: | Expression of the midnolin gene is developmentally regulated: it is strongly expressed at the mesencephalon (midbrain) of the embryo in day 12.5 (E12.5) mice. The midnolin encodes a protein of 508 amino acid, (aa), which contains a Ubiquitin-like domain. The intracellular distribution of the midnolin was studied by using midnolin-green fluorescent protein (GFP) fusion proteins. Midnolin was found to be localized in the nucleus and nucleolus, but not in the cytoplasm. The nucleolar localization signal was determined to be a 28aa peptide located at the C-terminal region of the midnolin. May be involved in regulation of genes related to neurogenesis in the nucleolus |
Synonyms: | Midnolin |
UniProt Protein Function: | MIDN: May be involved in regulation of genes related to neurogenesis in the nucleolus. |
UniProt Protein Details: | Protein type:Nucleolus Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: nucleolus; cytosol Molecular Function:kinase binding Biological Process: negative regulation of glucokinase activity; negative regulation of insulin secretion |
UniProt Code: | Q504T8 |
NCBI GenInfo Identifier: | 296437369 |
NCBI Gene ID: | 90007 |
NCBI Accession: | Q504T8.2 |
UniProt Related Accession: | Q504T8 |
Molecular Weight: | |
NCBI Full Name: | Midnolin |
NCBI Synonym Full Names: | midnolin |
NCBI Official Symbol: | MIDN |
NCBI Protein Information: | midnolin |
UniProt Protein Name: | Midnolin |
UniProt Synonym Protein Names: | Midbrain nucleolar protein |
Protein Family: | Midnolin |
UniProt Gene Name: | MIDN |
UniProt Entry Name: | MIDN_HUMAN |