MICU1 Polyclonal Antibody (CAB21948)
- SKU:
- CAB21948
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | MICU1 Polyclonal Antibody |
| Product Code: | CAB21948 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | OVCAR3, A-431, 293T |
| Cellular Location: | mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial membrane, mitochondrion |
This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 105-255 of human MICU1 (NP_001182447.1). |
| Sequence: | GFRDR KVMEY ENRIR AYSTP DKIFR YFATL KVISE PGEAE VFMTP EDFVR SITPN EKQPE HLGLD QYIIK RFDGK KISQE REKFA DEGSI FYTLG ECGLI SFSDY IFLTT VLSTP QRNFE IAFKM FDLNG DGEVD MEEFE QVQSI IRSQT S |
| Synonyms: | CALC, EFHA3, MPXPS, CBARA1, ara CALC |
| Calculated MW: | 54kDa |
| Observed MW: | 46kDa |
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