Mgll Antibody (PACO53698)
- SKU:
- PACO53698
- Product Type:
- Antibody
- Reactivity:
- Rat
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Mgll Antibody (PACO53698) |
| Antibody SKU: | PACO53698 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
| Species Reactivity: | Rat, Mouse |
| Immunogen: | Recombinant Rat Monoglyceride lipase protein (1-303AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: Rat lung tissue, Mouse brain tissue. All lanes: Mgll antibody at 2.8µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 34 kDa. Observed band size: 34 kDa. |
| Background: | Converts monoacylglycerides to free fatty acid, and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain. Regulates the levels of fatty acid, that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth. |
| Synonyms: | Monoglyceride lipase (MGL) (EC 3.1.1.23) (Monoacylglycerol lipase) (MAGL), Mgll, Mgl2 |
| UniProt Protein Function: | Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain. Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth. |
| UniProt Protein Details: | |
| NCBI Summary: | serine hydrolase that converts monoglycerides to fatty acid and glycerol; may play a role in retrograde signaling at central synapses and other forms of short-range neuronal communication [RGD, Feb 2006] |
| UniProt Code: | Q8R431 |
| NCBI GenInfo Identifier: | 19923092 |
| NCBI Gene ID: | 29254 |
| NCBI Accession: | NP_612511.1 |
| UniProt Secondary Accession: | Q8R431,Q32PZ2 |
| UniProt Related Accession: | Q8R431 |
| Molecular Weight: | 33,500 Da |
| NCBI Full Name: | monoglyceride lipase |
| NCBI Synonym Full Names: | monoglyceride lipase |
| NCBI Official Symbol: | Mgll |
| NCBI Official Synonym Symbols: | MAGL |
| NCBI Protein Information: | monoglyceride lipase |
| UniProt Protein Name: | Monoglyceride lipase |
| UniProt Synonym Protein Names: | Monoacylglycerol lipase; MAGL |
| Protein Family: | Monoglyceride lipase |
| UniProt Gene Name: | Mgll |
| UniProt Entry Name: |
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