Description
Product Name: | MESP2 Polyclonal Antibody |
Product Code: | CAB10353 |
Reactivity: | Human |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:2000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Cellular Location: | Nucleus |
This gene encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. This gene is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites. This gene also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm. Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02).
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 218-397 of human MESP2 (NP_001035047.1). |
Sequence: | ASWGS PSACP GAQAA PERLG RGVHD TDPWA TPPYC PKIQS PPYSS QGTTS DASLW TPPQG CPWTQ SSPEP RNPPV PWTAA PATLE LAAVY QGLSV SPEPC LSLGA PSLLP HPSCQ RLQPQ TPGRC WSHSA EVVPN SEDQG PGAAF QLSEA SPPQS SGLRF SGCPE LWQED LEGAR LGIFY |
Synonyms: | SCDO2, bHLHc6 |
Calculated MW: | 42kDa |
Observed MW: | Refer to figures |