MEOX2 Antibody (PACO53314)
- SKU:
- PACO53314
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MEOX2 Antibody (PACO53314) |
| Antibody SKU: | PACO53314 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Homeobox protein MOX-2 protein (94-193AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: RAW264.7 whole cell lysate. All lanes: MEOX2 antibody at 5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 34 kDa. Observed band size: 34 kDa. |
| Background: | Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development (By similarity). Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle. |
| Synonyms: | Homeobox protein MOX-2 (Growth arrest-specific homeobox) (Mesenchyme homeobox 2), MEOX2, GAX MOX2 |
| UniProt Protein Function: | MEOX2: Role in mesoderm induction and its earliest regional specification, somitogenesis, and myogenic and sclerotomal differentiation. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 7p22.1-p21.3 Cellular Component: cytoplasm; nucleus Molecular Function:protein binding; sequence-specific DNA binding; transcription factor activity Biological Process: blood circulation; multicellular organismal development; positive regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer's disease. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P50222 |
| NCBI GenInfo Identifier: | 93141286 |
| NCBI Gene ID: | 4223 |
| NCBI Accession: | P50222.2 |
| UniProt Secondary Accession: | P50222,O75263, Q9UPL6, B2R8I7, |
| UniProt Related Accession: | P50222 |
| Molecular Weight: | 33,594 Da |
| NCBI Full Name: | Homeobox protein MOX-2 |
| NCBI Synonym Full Names: | mesenchyme homeobox 2 |
| NCBI Official Symbol: | MEOX2 |
| NCBI Official Synonym Symbols: | GAX; MOX2 |
| NCBI Protein Information: | homeobox protein MOX-2 |
| UniProt Protein Name: | Homeobox protein MOX-2 |
| UniProt Synonym Protein Names: | Growth arrest-specific homeobox; Mesenchyme homeobox 2 |
| Protein Family: | Homeobox protein |
| UniProt Gene Name: | MEOX2 |
| UniProt Entry Name: | MEOX2_HUMAN |
| Antibodies | ELISA Kits |
| MEOX2 Antibody (PACO06649) | MEOX2 Colorimetric Cell-Based ELISA |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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