MEGF8 Antibody (PACO59193)
- SKU:
- PACO59193
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MEGF8 Antibody (PACO59193) |
| Antibody SKU: | PACO59193 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Multiple epidermal growth factor-like domains protein 8 protein (495-663AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO59193 diluted at 1:200 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | Immunofluorescence staining of HepG2 cells with PACO59193 at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | extracellular exosome, nucleus, BMP signaling pathway, cell migration involved in gastrulation, craniofacial suture morphogenesis, determination of digestive tract left/right asymmetry, determination of heart left/right asymmetry, embryonic heart tube left/right pattern formation, embryonic heart tube morphogenesis, embryonic limb morphogenesis |
| Synonyms: | Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4), MEGF8, C19orf49 EGFL4 KIAA0817 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a single-pass type I membrane protein of unknown function that contains several EGF-like domains, Kelch repeats, and PSI domains. Defects in this gene are a cause of Carpenter syndrome 2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012] |
| UniProt Code: | Q7Z7M0 |
| NCBI GenInfo Identifier: | 429836859 |
| NCBI Gene ID: | 1954 |
| NCBI Accession: | NP_001258867.1 |
| UniProt Secondary Accession: | Q7Z7M0,O75097, A8KAY0 |
| UniProt Related Accession: | Q7Z7M0 |
| Molecular Weight: | 295,934 Da |
| NCBI Full Name: | multiple epidermal growth factor-like domains protein 8 isoform 1 |
| NCBI Synonym Full Names: | multiple EGF like domains 8 |
| NCBI Official Symbol: | MEGF8 |
| NCBI Official Synonym Symbols: | SBP1; CRPT2; EGFL4; C19orf49 |
| NCBI Protein Information: | multiple epidermal growth factor-like domains protein 8 |
| UniProt Protein Name: | Multiple epidermal growth factor-like domains protein 8 |
| UniProt Synonym Protein Names: | Epidermal growth factor-like protein 4; EGF-like protein 4 |
| Protein Family: | Multiple epidermal growth factor-like domains protein |
| UniProt Gene Name: | MEGF8 |
| UniProt Entry Name: |
| Antibodies |
| MEGF8 Antibody (PACO00740) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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