MED37A Antibody (PACO62115)
- SKU:
- PACO62115
- Product Type:
- Antibody
- Reactivity:
- Plant - Arabidopsis
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MED37A Antibody (PACO62115) |
| Antibody SKU: | PACO62115 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
| Species Reactivity: | Arabidopsis thaliana |
| Immunogen: | Recombinant Arabidopsis thaliana Mediator of RNA polymerase II transcription subunit 37a protein (28-669AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: Arabidopsis thaliana leaf tissue. All lanes: MED37A antibody at 1:1000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 74 kDa. Observed band size: 74 kDa. |
| Background: | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors. |
| Synonyms: | Mediator of RNA polymerase II transcription subunit 37a (Heat shock 70 kDa protein 11) (Heat shock protein 70-11) (AtHsp70-11) (Luminal-binding protein 1) (AtBP1) (BiP1), MED37A, BIP1 HSP70-11 MED37_5 |
| UniProt Protein Function: | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors. |
| UniProt Protein Details: | |
| NCBI Summary: | Encodes the luminal binding protein BiP, an ER-localized member of the HSP70 family. BiP is composed of an N-terminal ATP binding domain and a C-terminal domain that binds to hydrophobic patches on improperly/incompletely folded proteins in an ATP-dependent manner. Involved in polar nuclei fusion during proliferation of endosperm nuclei. |
| UniProt Code: | Q9LKR3 |
| NCBI GenInfo Identifier: | 15241844 |
| NCBI Gene ID: | 832950 |
| NCBI Accession: | NP_198206.1 |
| UniProt Secondary Accession: | Q9LKR3,Q41928, Q56Y82 |
| UniProt Related Accession: | Q9LKR3 |
| Molecular Weight: | 73,629 Da |
| NCBI Full Name: | heat shock protein 70 (Hsp 70) family protein |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | BIP1 |
| NCBI Official Synonym Symbols: | T26D3.10; T26D3_10 |
| NCBI Protein Information: | heat shock protein 70 (Hsp 70) family protein |
| UniProt Protein Name: | Mediator of RNA polymerase II transcription subunit 37a |
| UniProt Synonym Protein Names: | Heat shock 70 kDa protein 11; Heat shock protein 70-11; AtHsp70-11; Luminal-binding protein 1; AtBP1; BiP1 |
| Protein Family: | Mediator of RNA polymerase II transcription |
| UniProt Gene Name: | MED37A |
| UniProt Entry Name: |
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