MED13L Antibody (PACO03697)
- SKU:
- PACO03697
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MED13L Antibody |
| Antibody SKU: | PACO03697 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | synthesized peptide derived from the Internal region of human TRAP240. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | MED13L; KIAA1025; Mediator of RNA polymerase II transcription subunit 13-like; Mediator complex subunit 13-like; Thyroid hormone receptor-associated protein 2; Thyroid hormone receptor-associated protein complex 240 kDa component-like |
| UniProt Protein Function: | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway. |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a subunit of the Mediator complex, a large complex of proteins that functions as a transcriptional coactivator for most RNA polymerase II-transcribed genes. The encoded protein is involved in early development of the heart and brain. Defects in this gene are a cause of transposition of the great arteries, dextro-looped (DTGA).[provided by RefSeq, Jul 2010] |
| UniProt Code: | Q71F56 |
| NCBI GenInfo Identifier: | 44771211 |
| NCBI Gene ID: | 23389 |
| NCBI Accession: | NP_056150.1 |
| UniProt Secondary Accession: | Q71F56,Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5, A1L469 |
| UniProt Related Accession: | Q71F56 |
| Molecular Weight: | 242,602 Da |
| NCBI Full Name: | mediator of RNA polymerase II transcription subunit 13-like |
| NCBI Synonym Full Names: | mediator complex subunit 13 like |
| NCBI Official Symbol: | MED13L |
| NCBI Official Synonym Symbols: | MRFACD; THRAP2; TRAP240L; PROSIT240 |
| NCBI Protein Information: | mediator of RNA polymerase II transcription subunit 13-like |
| UniProt Protein Name: | Mediator of RNA polymerase II transcription subunit 13-like |
| UniProt Synonym Protein Names: | Mediator complex subunit 13-like; Thyroid hormone receptor-associated protein 2; Thyroid hormone receptor-associated protein complex 240 kDa component-like |
| Protein Family: | Mediator of RNA polymerase II transcription |
| UniProt Gene Name: | MED13L |
| UniProt Entry Name: |
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