MED12L Antibody (PACO10438)
- SKU:
- PACO10438
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MED12L Antibody (PACO10438) |
| Antibody SKU: | PACO10438 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human MED12L |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | mediator complex subunit 12-like;MED12L;FLJ46288;KIAA1635;NOPAR;TNRC11L;TRALP;TRALPUSH ; |
| UniProt Protein Function: | MED12L: May be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Belongs to the Mediator complex subunit 12 family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Transcription initiation complexChromosomal Location of Human Ortholog: 3q25.1Cellular Component: Srb-mediator complexMolecular Function: beta-catenin binding; transcription factor bindingBiological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is part of the Mediator complex, which is involved in transcriptional coactivation of nearly all RNA polymerase II-dependent genes. The Mediator complex links gene-specific transcriptional activators with the basal transcription machinery. [provided by RefSeq, May 2010] |
| UniProt Code: | Q86YW9 |
| NCBI GenInfo Identifier: | 93277088 |
| NCBI Gene ID: | 116931 |
| NCBI Accession: | NP_443728.3 |
| UniProt Secondary Accession: | Q86YW9,Q96PC7, Q96PC8, Q9H9M5, Q9HCD7, Q9UI69 |
| UniProt Related Accession: | Q86YW9 |
| Molecular Weight: | 240,032 Da |
| NCBI Full Name: | mediator of RNA polymerase II transcription subunit 12-like protein |
| NCBI Synonym Full Names: | mediator complex subunit 12-like |
| NCBI Official Symbol: | MED12L |
| NCBI Official Synonym Symbols: | NOPAR; TRALP; TNRC11L; TRALPUSH |
| NCBI Protein Information: | mediator of RNA polymerase II transcription subunit 12-like protein |
| UniProt Protein Name: | Mediator of RNA polymerase II transcription subunit 12-like protein |
| UniProt Synonym Protein Names: | Mediator complex subunit 12-like protein; Thyroid hormone receptor-associated-like protein; Trinucleotide repeat-containing gene 11 protein-like |
| Protein Family: | Mediator of RNA polymerase II transcription |
| UniProt Gene Name: | MED12L |
| UniProt Entry Name: | MD12L_HUMAN |
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