MECR Antibody (PACO42106)
- SKU:
- PACO42106
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MECR Antibody (PACO42106) |
| Antibody SKU: | PACO42106 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human, Rat |
| Immunogen: | Recombinant Human Trans-2-enoyl-CoA reductase, mitochondrial protein (211-373AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: Rat heart tissue. All lanes: MECR antibody at 3.3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 41, 33 kDa. Observed band size: 41 kDa. |
 | Immunohistochemistry analysis of human liver cancer using PACO42106 at dilution of 1:100. |
| Background: | Oxidoreductase with a preference for short and medium chain substrates, including trans-2-hexenoyl-CoA (C6), trans-2-decenoyl-CoA (C10), and trans-2-hexadecenoyl-CoA (C16). May play a role in mitochondrial fatty acid, synthesis. |
| Synonyms: | Enoyl-[acyl-carrier-protein] reductase, mitochondrial (EC 1.3.1.104) (2-enoyl thioester reductase) (Nuclear receptor-binding factor 1) (HsNrbf-1) (NRBF-1), MECR, NBRF1 |
| UniProt Protein Function: | MECR: Catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH-dependent manner with preference to medium chain length substrate. May have a role in the mitochondrial synthesis of fatty acids. Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Lipid Metabolism - fatty acid elongation in mitochondria; Oxidoreductase; EC 1.3.1.38 Chromosomal Location of Human Ortholog: 1p35.3 Cellular Component: mitochondrion; nucleus Molecular Function:zinc ion binding; trans-2-enoyl-CoA reductase (NADPH) activity Biological Process: fatty acid metabolic process; fatty acid biosynthetic process |
| UniProt Code: | Q9BV79 |
| NCBI GenInfo Identifier: | 334302832 |
| NCBI Gene ID: | 51102 |
| NCBI Accession: | Q9BV79.2 |
| UniProt Secondary Accession: | Q9BV79,Q5SYU0, Q5SYU1, Q5SYU2, Q6IBU9, Q9Y373, B3KT72 |
| UniProt Related Accession: | Q9BV79 |
| Molecular Weight: | 373 |
| NCBI Full Name: | Trans-2-enoyl-CoA reductase, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial trans-2-enoyl-CoA reductase |
| NCBI Official Symbol: | MECR |
| NCBI Official Synonym Symbols: | NRBF1; CGI-63; FASN2B |
| NCBI Protein Information: | trans-2-enoyl-CoA reductase, mitochondrial; nuclear receptor binding factor 1; mitochondrial 2-enoyl thioester reductase; homolog of yeast 2-enoyl thioester reductase |
| UniProt Protein Name: | Trans-2-enoyl-CoA reductase, mitochondrial |
| UniProt Synonym Protein Names: | Nuclear receptor-binding factor 1; HsNrbf-1; NRBF-1 |
| UniProt Gene Name: | MECR |
| UniProt Entry Name: | MECR_HUMAN |
| Antibodies |
| MECR Antibody (PACO10436) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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