Description
| Antibody Name: | MECR Antibody (PACO10436) |
| Antibody SKU: | PACO10436 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human MECR |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | mitochondrial trans-2-enoyl-CoA reductase;MECR;CGI-63;FASN2B;NRBF1 ; |
| UniProt Protein Function: | MECR: Catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH-dependent manner with preference to medium chain length substrate. May have a role in the mitochondrial synthesis of fatty acids. Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Lipid Metabolism - fatty acid elongation in mitochondria; Oxidoreductase; EC 1.3.1.38 Chromosomal Location of Human Ortholog: 1p35.3 Cellular Component: mitochondrion; nucleus Molecular Function:zinc ion binding; trans-2-enoyl-CoA reductase (NADPH) activity Biological Process: fatty acid metabolic process; fatty acid biosynthetic process |
| UniProt Code: | Q9BV79 |
| NCBI GenInfo Identifier: | 334302832 |
| NCBI Gene ID: | 51102 |
| NCBI Accession: | Q9BV79.2 |
| UniProt Secondary Accession: | Q9BV79,Q5SYU0, Q5SYU1, Q5SYU2, Q6IBU9, Q9Y373, B3KT72 |
| UniProt Related Accession: | Q9BV79 |
| Molecular Weight: | 373 |
| NCBI Full Name: | Trans-2-enoyl-CoA reductase, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial trans-2-enoyl-CoA reductase |
| NCBI Official Symbol: | MECR |
| NCBI Official Synonym Symbols: | NRBF1; CGI-63; FASN2B |
| NCBI Protein Information: | trans-2-enoyl-CoA reductase, mitochondrial; nuclear receptor binding factor 1; mitochondrial 2-enoyl thioester reductase; homolog of yeast 2-enoyl thioester reductase |
| UniProt Protein Name: | Trans-2-enoyl-CoA reductase, mitochondrial |
| UniProt Synonym Protein Names: | Nuclear receptor-binding factor 1; HsNrbf-1; NRBF-1 |
| UniProt Gene Name: | MECR |
| UniProt Entry Name: | MECR_HUMAN |