Mcpt4 Antibody (PACO34310)
- SKU:
- PACO34310
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Mcpt4 Antibody (PACO34310) |
| Antibody SKU: | PACO34310 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse Mast cell protease 4 protein (21-246AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Has chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4- |-Ile-5' bond of angiotensin I and the 'Phe-20- |-Ala-21' bond of amyloid beta-protein, and is less active towards the 'Phe-8- |-His-9' bond of angiotensin I and the 'Phe-4- |-Ala-5' and 'Tyr-10- |-Glu-11' bonds of amyloid beta-protein. Involved in thrombin regulation and fibronectin processing. |
| Synonyms: | Mast cell protease 4 (mMCP-4) (EC 3.4.21.-) (MSMCP) (Myonase) (Serosal mast cell protease), Mcpt4 |
| UniProt Protein Function: | Mcpt4: Has chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4-|-Ile-5' bond of angiotensin I and the 'Phe-20-|-Ala-21' bond of amyloid beta- protein, and is less active towards the 'Phe-8-|-His-9' bond of angiotensin I and the 'Phe-4-|-Ala-5' and 'Tyr-10-|-Glu-11' bonds of amyloid beta-protein. Involved in thrombin regulation and fibronectin processing. Belongs to the peptidase S1 family. Granzyme subfamily.Protein type: EC 3.4.21.-; ProteaseCellular Component: cytoplasm; intracellular; intracellular membrane-bound organelleMolecular Function: hydrolase activity; peptidase activity; serine-type endopeptidase activity; serine-type peptidase activityBiological Process: immune response; protein processing; proteolysis; regulation of angiotensin levels in blood |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P21812 |
| NCBI GenInfo Identifier: | 114205406 |
| NCBI Gene ID: | 17227 |
| NCBI Accession: | NP_034909.2 |
| UniProt Secondary Accession: | P21812,Q9EPQ9, Q9EQT2 |
| UniProt Related Accession: | P21812 |
| Molecular Weight: | 27,204 Da |
| NCBI Full Name: | mast cell protease 4 |
| NCBI Synonym Full Names: | mast cell protease 4 |
| NCBI Official Symbol: | Mcpt4 |
| NCBI Official Synonym Symbols: | Mcp4; Mcp-4; MMCP-4; MMCP-4A; MMCP-4B |
| NCBI Protein Information: | mast cell protease 4 |
| UniProt Protein Name: | Mast cell protease 4 |
| UniProt Synonym Protein Names: | MSMCP; Myonase; Serosal mast cell protease |
| Protein Family: | Mast cell protease |
| UniProt Gene Name: | Mcpt4 |
| UniProt Entry Name: | MCPT4_MOUSE |
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