MARVELD3 Antibody (PACO60264)
- SKU:
- PACO60264
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MARVELD3 Antibody (PACO60264) |
| Antibody SKU: | PACO60264 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human MARVEL domain-containing protein 3 protein (1-189AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescence staining of Hela cells with PACO60264 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | As a component of tight junctions, plays a role in paracellular ion conductivity. |
| Synonyms: | MARVEL domain-containing protein 3, MARVELD3, MRVLDC3 |
| UniProt Protein Function: | MARVELD3: As a component of tight junctions, plays a role in paracellular ion conductivity. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 16q22.2Cellular Component: cytoplasmic vesicle; integral to membrane; tight junctionMolecular Function: mitogen-activated protein kinase kinase kinase binding; protein bindingBiological Process: intercellular junction assembly and maintenance; negative regulation of epithelial cell proliferation; negative regulation of JNK cascade; response to osmotic stress |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96A59 |
| NCBI GenInfo Identifier: | 65293358 |
| NCBI Gene ID: | 91862 |
| NCBI Accession: | NP_443090.2 |
| UniProt Secondary Accession: | Q96A59,Q96MJ4, A8K820, H3BQM5 |
| UniProt Related Accession: | Q96A59 |
| Molecular Weight: | 17,704 Da |
| NCBI Full Name: | MARVEL domain-containing protein 3 isoform 2 |
| NCBI Synonym Full Names: | MARVEL domain containing 3 |
| NCBI Official Symbol: | MARVELD3 |
| NCBI Official Synonym Symbols: | MARVD3; MRVLDC3 |
| NCBI Protein Information: | MARVEL domain-containing protein 3 |
| UniProt Protein Name: | MARVEL domain-containing protein 3 |
| UniProt Synonym Protein Names: | |
| Protein Family: | MARVEL domain-containing protein |
| UniProt Gene Name: | MARVELD3 |
| UniProt Entry Name: | MALD3_HUMAN |
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