MARK1/MARK2/MARK3/MARK4 Antibody (PACO01042)
- SKU:
- PACO01042
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Reactivity:
- NHP - Monkey
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MARK1/MARK2/MARK3/MARK4 Antibody |
| Antibody SKU: | PACO01042 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse, Rat, Monkey |
| Immunogen: | synthesized peptide derived from human MARK1/2/3/4 around the non-phosphorylation site of T215. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | MARK1; KIAA1477; MARK; Serine/threonine-protein kinase MARK1; MAP/microtubule affinity-regulating kinase 1; PAR1 homolog c; Par-1c; Par1c; MARK2; EMK1; Serine/threonine-protein kinase MARK2; ELKL motif kinase 1; EMK-1; MAP/microtubule affin |
| UniProt Protein Function: | MARK1: a member of the CAMKL family of protein kinases. The MARK group of kinases is apparently involved in the control of cell polarity, microtubule stability and cancer. MARK1 forms a tight association with Tau in neurofibrillary tangles in Alzheimer disease tissue. |
| UniProt Protein Details: | Protein type:Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; Kinase, protein; EC 2.7.11.1; EC 2.7.11.26; CAMK group; CAMKL family; MARK subfamily Chromosomal Location of Human Ortholog: 1q41 Cellular Component: cytoplasm; cytoskeleton; microtubule cytoskeleton; plasma membrane Molecular Function:ATP binding; magnesium ion binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylserine binding; protein serine/threonine kinase activity; tau-protein kinase activity Biological Process: cytoskeleton organization and biogenesis; neuron migration; protein amino acid phosphorylation; Wnt receptor signaling pathway |
| UniProt Code: | Q9P0L2 |
| NCBI GenInfo Identifier: | 124056494 |
| NCBI Gene ID: | 4139 |
| NCBI Accession: | Q9P0L2.2 |
| UniProt Secondary Accession: | Q9P0L2,Q2HIY1, Q5VTF9, Q5VTG0, Q96SW9, Q9P251, D3DTB0 D3DTB1, |
| UniProt Related Accession: | Q9P0L2 |
| Molecular Weight: | 84,911 Da |
| NCBI Full Name: | Serine/threonine-protein kinase MARK1 |
| NCBI Synonym Full Names: | microtubule affinity regulating kinase 1 |
| NCBI Official Symbol: | MARK1 |
| NCBI Official Synonym Symbols: | MARK; Par1c; Par-1c |
| NCBI Protein Information: | serine/threonine-protein kinase MARK1 |
| UniProt Protein Name: | Serine/threonine-protein kinase MARK1 |
| UniProt Synonym Protein Names: | MAP/microtubule affinity-regulating kinase 1; PAR1 homolog c; Par-1c; Par1c |
| Protein Family: | Serine/threonine-protein kinase |
| UniProt Gene Name: | MARK1 |
| UniProt Entry Name: | MARK1_HUMAN |
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