Description
Product Name: | MARCKSL1 Polyclonal Antibody |
Product Code: | CAB24471 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | 293T, SH-SY5Y, Mouse thymus, Rat testis |
Cellular Location: | Cell membrane, Cytoplasm, Lipid-anchor, Membrane |
This gene encodes a member of the myristoylated alanine-rich C-kinase substrate (MARCKS) family. Members of this family play a role in cytoskeletal regulation, protein kinase C signaling and calmodulin signaling. The encoded protein affects the formation of adherens junction. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on the long arm of chromosomes 6 and 10.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 95-195 of human MARCKSL1 (NP_075385.1). |
Sequence: | KKPFK LSGLS FKRNR KEGGG DSSAS SPTEE EQEQG EIGAC SDEGT AQEGK AAATP ESQEP QAKGA EASAA SEEEA GPQAT EPSTP SGPES GPTPA SAEQN E |
Synonyms: | MARCKSL1, F52, MACMARCKS, MLP, MLP1, MRP, MARCKS like 1 |
Calculated MW: | 19kDa |
Observed MW: | 40kDa |