MAP1LC3B2 Antibody (PACO47530)
- SKU:
- PACO47530
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MAP1LC3B2 Antibody (PACO47530) |
| Antibody SKU: | PACO47530 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Microtubule-associated proteins 1A/1B light chain 3 β 2 protein (1-47AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescent analysis of Hela cells using PACO47530 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity). |
| Synonyms: | Microtubule-associated proteins 1A/1B light chain 3 β 2 (Microtubule-associated proteins 1A/1B light chain 3B-like), MAP1LC3B2 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | A6NCE7 |
| NCBI GenInfo Identifier: | 12383056 |
| NCBI Gene ID: | 81631 |
| NCBI Accession: | NP_073729.1 |
| UniProt Secondary Accession: | A6NCE7,A6NCE7 |
| UniProt Related Accession: | A6NCE7,Q9GZQ8 |
| Molecular Weight: | 125 |
| NCBI Full Name: | microtubule-associated proteins 1A/1B light chain 3B |
| NCBI Synonym Full Names: | microtubule-associated protein 1 light chain 3 beta |
| NCBI Official Symbol: | MAP1LC3B |
| NCBI Official Synonym Symbols: | LC3B; ATG8F; MAP1LC3B-a; MAP1A/1BLC3 |
| NCBI Protein Information: | microtubule-associated proteins 1A/1B light chain 3B; MAP1A/MAP1B LC3 B; MAP1A/MAP1B light chain 3 B; MAP1 light chain 3-like protein 2; autophagy-related ubiquitin-like modifier LC3 B |
| UniProt Protein Name: | Microtubule-associated proteins 1A/1B light chain 3B |
| UniProt Synonym Protein Names: | Autophagy-related protein LC3 B; Autophagy-related ubiquitin-like modifier LC3 B; MAP1 light chain 3-like protein 2; MAP1A/MAP1B light chain 3 B; MAP1A/MAP1B LC3 B; Microtubule-associated protein 1 light chain 3 beta |
| Protein Family: | |
| UniProt Gene Name: | MAP1LC3B |
| UniProt Entry Name: | MLP3B_HUMAN |
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