Description
Product Name: | MAP1LC3A Monoclonal Antibody |
Product Code: | CAB22428 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC0319 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, ELISA |
Key Applications: | Western blotting, Immunohistochemistry |
Recommended Dilution: | WB 1:500-1:2000, IHC-P 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Cellular Location: | Cytoplasm, Cytoplasmic vesicle, Endomembrane system, Lipid-anchor, autophagosome, autophagosome membrane, cytoskeleton |
MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 42-121 of human LC3A (Q9H492). |
Sequence: | KQLPV LDKTK FLVPD HVNMS ELVKI IRRRL QLNPT QAFFL LVNQH SMVSV STPIA DIYEQ EKDED GFLYM VYASQ ETFGF |
Synonyms: | LC3, LC3A, ATG8E, MAP1ALC3, MAP1BLC3 |
Calculated MW: | 14kDa |
Observed MW: | Refer to figures |