MAGI2 Antibody (PACO55198)
- SKU:
- PACO55198
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MAGI2 Antibody (PACO55198) |
| Antibody SKU: | PACO55198 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 protein (1308-1455AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human brain tissue using PACO55198 at dilution of 1:100. |
 | Immunofluorescent analysis of A549 cells using PACO55198 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. |
| Synonyms: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Atrophin-1-interacting protein 1) (AIP-1) (Atrophin-1-interacting protein A) (Membrane-associated guanylate kinase inverted 2) (MAGI-2), MAGI2, ACVRINP1 AIP1 KIAA0705 |
| UniProt Protein Function: | Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q86UL8 |
| NCBI GenInfo Identifier: | 88909269 |
| NCBI Gene ID: | 9863 |
| NCBI Accession: | Q86UL8.3 |
| UniProt Secondary Accession: | Q86UL8,O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1 A4D1C1, A7E2C3 |
| UniProt Related Accession: | Q86UL8 |
| Molecular Weight: | 157,236 Da |
| NCBI Full Name: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 |
| NCBI Synonym Full Names: | membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| NCBI Official Symbol: | MAGI2 |
| NCBI Official Synonym Symbols: | AIP1; AIP-1; ARIP1; SSCAM; MAGI-2; ACVRIP1 |
| NCBI Protein Information: | membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 |
| UniProt Protein Name: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 |
| UniProt Synonym Protein Names: | Atrophin-1-interacting protein 1; AIP-1; Atrophin-1-interacting protein A; Membrane-associated guanylate kinase inverted 2; MAGI-2 |
| Protein Family: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein |
| UniProt Gene Name: | MAGI2 |
| UniProt Entry Name: | MAGI2_HUMAN |
| Antibodies |
| MAGI2 Antibody (PACO05831) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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