MAGI2 Antibody (PACO05831)
- SKU:
- PACO05831
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MAGI2 Antibody (PACO05831) |
| Antibody SKU: | PACO05831 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:20000, WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from the Internal region of human MAGI-2. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | MAGI2; ACVRINP1; AIP1; KIAA0705; Membrane-associated guanylate kinase; WW and PDZ domain-containing protein 2; Atrophin-1-interacting protein 1; AIP-1; Atrophin-1-interacting protein A; Membrane-associated guanylate kinase inverted 2; MAGI- |
| UniProt Protein Function: | Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q86UL8 |
| NCBI GenInfo Identifier: | 88909269 |
| NCBI Gene ID: | 9863 |
| NCBI Accession: | Q86UL8.3 |
| UniProt Secondary Accession: | Q86UL8,O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1 A4D1C1, A7E2C3 |
| UniProt Related Accession: | Q86UL8 |
| Molecular Weight: | 157,236 Da |
| NCBI Full Name: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 |
| NCBI Synonym Full Names: | membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| NCBI Official Symbol: | MAGI2 |
| NCBI Official Synonym Symbols: | AIP1; AIP-1; ARIP1; SSCAM; MAGI-2; ACVRIP1 |
| NCBI Protein Information: | membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 |
| UniProt Protein Name: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 |
| UniProt Synonym Protein Names: | Atrophin-1-interacting protein 1; AIP-1; Atrophin-1-interacting protein A; Membrane-associated guanylate kinase inverted 2; MAGI-2 |
| Protein Family: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein |
| UniProt Gene Name: | MAGI2 |
| UniProt Entry Name: | MAGI2_HUMAN |
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