MAGI1 Antibody (PACO60316)
- SKU:
- PACO60316
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MAGI1 Antibody (PACO60316) |
| Antibody SKU: | PACO60316 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 protein (1234-1367AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescence staining of HepG2 cells with PACO60316 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | May play a role as scaffolding protein at cell-cell junctions. May regulate acid, induced ASIC3 currents by modulating its expression at the cell surface (By similarity). |
| Synonyms: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (Atrophin-1-interacting protein 3) (AIP-3) (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Trinucleotide repeat-containing gene 19 protein) (WW domain-containing protein 3) (WWP3), MAGI1, AIP3 BAIAP1 BAP1 TNRC19 |
| UniProt Protein Function: | MAGI1: May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface. 7 isoforms of the human protein are produced by alternative splicing.Protein type: Motility/polarity/chemotaxis; Cell adhesionChromosomal Location of Human Ortholog: 3p14.1Cellular Component: nucleoplasm; tight junction; cell projection; cytoplasm; plasma membrane; intercellular junction; cell junctionMolecular Function: protein C-terminus binding; protein binding; protein complex scaffold; alpha-actinin binding; ATP bindingBiological Process: cell surface receptor linked signal transduction; protein complex assembly; cell adhesion |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a member of the membrane-associated guanylate kinase homologue (MAGUK) family. MAGUK proteins participate in the assembly of multiprotein complexes on the inner surface of the plasma membrane at regions of cell-cell contact. The product of this gene may play a role as scaffolding protein at cell-cell junctions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q96QZ7 |
| NCBI GenInfo Identifier: | 74272284 |
| NCBI Gene ID: | 9223 |
| NCBI Accession: | NP_001028229.1 |
| UniProt Secondary Accession: | Q96QZ7,O00309, O43863, O75085, Q96QZ8, Q96QZ9, A8K188 |
| UniProt Related Accession: | Q96QZ7 |
| Molecular Weight: | 164,581 Da |
| NCBI Full Name: | membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 isoform c |
| NCBI Synonym Full Names: | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| NCBI Official Symbol: | MAGI1 |
| NCBI Official Synonym Symbols: | AIP3; BAP1; WWP3; AIP-3; BAP-1; BAIAP1; MAGI-1; Magi1d; TNRC19 |
| NCBI Protein Information: | membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1; BAI1-associated protein 1; WW domain-containing protein 3; atrophin-1-interacting protein 3; membrane-associated guanylate kinase inverted 1; trinucleotide repeat-containing gene 19 protein |
| UniProt Protein Name: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 |
| UniProt Synonym Protein Names: | Atrophin-1-interacting protein 3; AIP-3; BAI1-associated protein 1; BAP-1; Membrane-associated guanylate kinase inverted 1; MAGI-1; Trinucleotide repeat-containing gene 19 protein; WW domain-containing protein 3; WWP3 |
| Protein Family: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein |
| UniProt Gene Name: | MAGI1 |
| UniProt Entry Name: | MAGI1_HUMAN |
| Antibodies |
| MAGI1 Antibody (PACO10347) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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