Description
Antibody Name: | MAGEB4 Antibody (PACO14672) |
Antibody SKU: | PACO14672 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:15-1:50 |
Species Reactivity: | Human |
Immunogen: | Fusion protein of human MAGEB4 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO14672(MAGEB4 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
![]() | Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human brain glioma tissue, Primary antibody: PACO14672(MAGEB4 Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO14672(MAGEB4 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68 sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEB genes are clustered on chromosome Xp22-p21. This gene sequence ends in the first intron of MAGEB1, another family member. This gene is expressed in testis. |
Synonyms: | melanoma antigen family B, 4 |
UniProt Protein Function: | MAGE-B4: |
UniProt Protein Details: | Protein type:Cancer Testis Antigen (CTA) Chromosomal Location of Human Ortholog: Xp21.3 |
NCBI Summary: | This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEB genes are clustered on chromosome Xp22-p21. This gene sequence ends in the first intron of MAGEB1, another family member. This gene is expressed in testis. [provided by RefSeq, Jul 2008] |
UniProt Code: | O15481 |
NCBI GenInfo Identifier: | 6016557 |
NCBI Gene ID: | 4115 |
NCBI Accession: | O15481.1 |
UniProt Secondary Accession: | O15481,P43366, O15479, Q96LZ2, Q96M61, |
UniProt Related Accession: | O15481 |
Molecular Weight: | 346 |
NCBI Full Name: | Melanoma-associated antigen B4 |
NCBI Synonym Full Names: | melanoma antigen family B, 4 |
NCBI Official Symbol: | MAGEB4 |
NCBI Official Synonym Symbols: | CT3.6 |
NCBI Protein Information: | melanoma-associated antigen B4; MAGE-B4 antigen; cancer/testis antigen family 3, member 6 |
UniProt Protein Name: | Melanoma-associated antigen B4 |
UniProt Synonym Protein Names: | MAGE-B4 antigen |
UniProt Gene Name: | MAGEB4 |
UniProt Entry Name: | MAGB4_HUMAN |
Antibodies |
MAGEB4 Antibody (PACO10341) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |