MAGEB18 Antibody (PACO19973)
- SKU:
- PACO19973
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MAGEB18 Antibody (PACO19973) |
| Antibody SKU: | PACO19973 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human MAGEB18 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO19973(MAGEB18 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO19973(MAGEB18 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors and, based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens that are expressed in tumors of different histologic types and in normal testis and placenta. MAGE-B18 (melanoma-associated antigen B18) is a 343 amino acid, protein that contains one MAGE domain and may be involved in tumorigenesis. The gene encoding MAGE-B18 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. |
| Synonyms: | melanoma antigen family B, 18 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96M61 |
| NCBI GenInfo Identifier: | 296435512 |
| NCBI Gene ID: | 286514 |
| NCBI Accession: | Q96M61.2 |
| UniProt Secondary Accession: | Q96M61 |
| UniProt Related Accession: | Q96M61 |
| Molecular Weight: | 343 |
| NCBI Full Name: | Melanoma-associated antigen B18 |
| NCBI Synonym Full Names: | melanoma antigen family B, 18 |
| NCBI Official Symbol: | MAGEB18 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | melanoma-associated antigen B18; MAGE-B18 antigen |
| UniProt Protein Name: | Melanoma-associated antigen B18 |
| UniProt Synonym Protein Names: | MAGE-B18 antigen |
| Protein Family: | |
| UniProt Gene Name: | MAGEB18 |
| UniProt Entry Name: | MAGBI_HUMAN |
| Antibodies |
| MAGEB18 Antibody (PACO10339) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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