MAGEA8 Antibody (PACO16644)
- SKU:
- PACO16644
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MAGEA8 Antibody (PACO16644) |
| Antibody SKU: | PACO16644 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human MAGEA8 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: A375 cells, human lung cancer tissue, Primary antibody: PACO16644(MAGEA8 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds. |
| Background: | This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
| Synonyms: | melanoma antigen family A, 8 |
| UniProt Protein Function: | Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2009] |
| UniProt Code: | P43361 |
| NCBI GenInfo Identifier: | 261878488 |
| NCBI Gene ID: | 4107 |
| NCBI Accession: | NP_001159872.1 |
| UniProt Secondary Accession: | P43361,Q9BUN9 |
| UniProt Related Accession: | P43361 |
| Molecular Weight: | 34 |
| NCBI Full Name: | melanoma-associated antigen 8 |
| NCBI Synonym Full Names: | MAGE family member A8 |
| NCBI Official Symbol: | MAGEA8 |
| NCBI Official Synonym Symbols: | CT1.8; MAGE8 |
| NCBI Protein Information: | melanoma-associated antigen 8 |
| UniProt Protein Name: | Melanoma-associated antigen 8 |
| UniProt Synonym Protein Names: | Cancer/testis antigen 1.8; CT1.8; MAGE-8 antigen |
| Protein Family: | |
| UniProt Gene Name: | MAGEA8 |
| UniProt Entry Name: |
| Antibodies |
| MAGEA8 Antibody (PACO10338) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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