Description
Antibody Name: | MAGEA5 Antibody (PACO28110) |
Antibody SKU: | PACO28110 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Melanoma-associated antigen 5 protein (1-124AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human melanoma using PACO28110 at dilution of 1:100. |
Background: | Not known, though may play a role tumor transformation or progression. In vitro promotes cell viability in melanoma cell lines. |
Synonyms: | Melanoma-associated antigen 5 (Cancer/testis antigen 1.5) (CT1.5) (MAGE-5 antigen), MAGEA5, MAGE5 |
UniProt Protein Function: | |
UniProt Protein Details: | |
NCBI Summary: | This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This MAGEA gene encodes a protein that is C-terminally truncated compared to other family members, and this gene can be alternatively interpreted to be a pseudogene. The protein is represented in this Gene record in accordance with the assumed protein-coding status defined in the literature. Read-through transcription exists between this gene and the upstream melanoma antigen family A, 10 (MAGEA10) gene. [provided by RefSeq, Oct 2011] |
UniProt Code: | P43359 |
NCBI GenInfo Identifier: | 80478226 |
NCBI Gene ID: | 4104 |
NCBI Accession: | BC109187 |
UniProt Secondary Accession: | P43359 |
UniProt Related Accession: | P43359 |
Molecular Weight: | |
NCBI Full Name: | Homo sapiens melanoma antigen family A, 5, mRNA |
NCBI Synonym Full Names: | MAGE family member A5 |
NCBI Official Symbol: | MAGEA5 |
NCBI Official Synonym Symbols: | CT1.5; MAGE5; MAGEA4 |
NCBI Protein Information: | melanoma-associated antigen 5 |
UniProt Protein Name: | |
UniProt Synonym Protein Names: | |
Protein Family: | |
UniProt Gene Name: | |
UniProt Entry Name: |
Antibodies |
MAGEA5 Antibody (PACO02887) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |