MAGEA10 Antibody (PACO16642)
- SKU:
- PACO16642
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MAGEA10 Antibody (PACO16642) |
| Antibody SKU: | PACO16642 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human MAGEA10 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: A375 cells, Primary antibody: PACO16642(MAGEA10 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO16642(MAGEA10 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. |
| Synonyms: | melanoma antigen family A, 10 |
| UniProt Protein Function: | MAGE-A10: Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.Chromosomal Location of Human Ortholog: Xq28Cellular Component: nucleus |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding the same protein have been found for this gene. Read-through transcription also exists between this gene and the downstream melanoma antigen family A, 5 (MAGEA5) gene.[provided by RefSeq] |
| UniProt Code: | P43363 |
| NCBI GenInfo Identifier: | 10567820 |
| NCBI Gene ID: | 4109 |
| NCBI Accession: | NP_066386.1 |
| UniProt Secondary Accession: | P43363 |
| UniProt Related Accession: | P43363 |
| Molecular Weight: | 40,780 Da |
| NCBI Full Name: | melanoma-associated antigen 10 |
| NCBI Synonym Full Names: | melanoma antigen family A, 10 |
| NCBI Official Symbol: | MAGEA10 |
| NCBI Official Synonym Symbols: | CT1.10; MAGE10; MGC10599 |
| NCBI Protein Information: | melanoma-associated antigen 10; MAGE-10 antigen; OTTHUMP00000025894; OTTHUMP00000025895; OTTHUMP00000025896; cancer/testis antigen 1.10; cancer/testis antigen family 1, member 10 |
| UniProt Protein Name: | Melanoma-associated antigen 10 |
| UniProt Synonym Protein Names: | Cancer/testis antigen 1.10; CT1.10; MAGE-10 antigen |
| Protein Family: | |
| UniProt Gene Name: | MAGEA10 |
| UniProt Entry Name: | MAGAA_HUMAN |
| Antibodies |
| MAGEA10 Antibody (PACO10334) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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