MAD1L1 Polyclonal Antibody
- SKU:
- CAB24666
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | MAD1L1 Polyclonal Antibody |
| Product Code: | CAB24666 |
| Reactivity: | Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Rat thymus |
| Cellular Location: | centrosome, cytoplasm, cytosol, mitotic spindle, mitotic spindle assembly checkpoint MAD1-MAD2 complex, nuclear pore nuclear basket, nucleus, spindle, spindle pole |
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAD1L1(NP_003541.2). |
| Sequence: | MEDLG ENTMV LSTLR SLNNF ISQRV EGGSG LDIST SAPGS LQMQY QQSMQ LEERA EQIRS KSHLI QVERE KMQME LSHKR ARVEL ERAAS TSARN YEREV |
| Synonyms: | MAD1, MVA7, PIG9, TP53I9, TXBP181 |
| Calculated MW: | 83kDa |
| Observed MW: | 83kDa |
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