M6PR Polyclonal Antibody

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SKU:
CAB21486
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
Applications:
IHC

Description

Product Name:M6PR Polyclonal Antibody
Product Code:CAB21486
Reactivity:Human, Mouse, Rat
Applications:Western blotting, Immunohistochemistry
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human, Mouse, Rat
Tested Applications:WB, IHC-P, ELISA
Key Applications:Western blotting, Immunohistochemistry
Recommended Dilution:WB 1:500-1:2000, IHC-P 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Cellular Location:Lysosome membrane, Single-pass type I membrane protein

This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 27-185 of human M6PR (NP_002346.1).
Sequence:TEEKT CDLVG EKGKE SEKEL ALVKR LKPLF NKSFE STVGQ GSDTY IYIFR VCREA GNHTS GAGLV QINKS NGKET VVGRL NETHI FNGSN WIMLI YKGGD EYDNH CGKEQ RRAVV MISCN RHTLA DNFNP VSEER GKVQD CFYLF EMDSS LACSP EISH
Synonyms:SMPR, MPR46, CD-MPR, MPR 46, MPR-46, CD-M6PR
Calculated MW:31kDa
Observed MW:Refer to figures
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