M Antibody (PACO63759)
- SKU:
- PACO63759
- Product Type:
- Antibody
- Reactivity:
- Virus
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | M Antibody (PACO63759) |
| Antibody SKU: | PACO63759 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Vesicular stomatitis Indiana virus |
| Immunogen: | Recombinant Vesicular stomatitis Indiana virus Matrix protein (1-237AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in Recombinant protein. All lanes: M antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 35 kDa. Observed band size: 35 kDa. |
| Background: | Plays a major role in assembly and budding of virion. Condensates the ribonucleocapsid core during virus assembly. Shut off cellular transcription by inhibiting mRNA nuclear export through direct interaction with host RAE1-NUP98 complex. This shut off presumably inhibit interferon signaling and thus establishment of antiviral state in virus infected cells. Induces cell-rounding, cytoskeleton disorganization and apoptosis in infected cell (By similarity). |
| Synonyms: | Matrix protein, M |
| UniProt Protein Function: | Plays a major role in assembly and budding of virion. Condensates the ribonucleocapsid core during virus assembly. Shut off cellular transcription by inhibiting mRNA nuclear export through direct interaction with host RAE1-NUP98 complex. This shut off presumably inhibit interferon signaling and thus establishment of antiviral state in virus infected cells. Induces cell-rounding, cytoskeleton disorganization and apoptosis in infected cell (). |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P04876 |
| NCBI GenInfo Identifier: | 138759 |
| NCBI Gene ID: | |
| NCBI Accession: | P04876.1 |
| UniProt Secondary Accession: | P04876 |
| UniProt Related Accession: | P04876 |
| Molecular Weight: | 28.8 |
| NCBI Full Name: | Matrix protein |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Matrix protein |
| UniProt Synonym Protein Names: | |
| Protein Family: | |
| UniProt Gene Name: | M |
| UniProt Entry Name: | MATRX_VSIVG |
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